Exposure, Absorption and Distribution of Xenobiotics
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Factors affecting the absorption and distribution of xenobiotics in the body. Elimination / Excretion.
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Metabolism of xenobiotics
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Oxidation reactions: dependent and independent cytochrome P450 monooxygenases. Reactions of reduction and hydrolysis. Conjugation Reactions. |
Oxidative stress and antioxidant defense
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Production of oxy-radicals and oxidative stress. Biological effects of reactive oxygen species. Antioxidant Cellular Defenses. |