Since ancient times, man has used biotechnological processes to obtain products of interest. Currently, the biotechnology sector is one of the areas that is experiencing the greatest growth, which entails the need to select, within a space of possibilities, those alternatives that, based on a predetermined criterion, allow meeting the desired objectives . The search for a formal approach to the design problem promotes the need to find mathematical models that fit the empirical data and that allow greater ease in the optimization and simulation of these processes. All this will result in greater efficiency and ease of control of the diversity of biotechnology-based processes. English Friendly subject: International students may request from the teachers: a) materials and bibliographic references in English, b) tutoring sessions in English, c) exams and assessments in English.