Educational guide 2018_19 Facultade de Bioloxía

Contents

Topic	Sub-topic
Organization of marine genomes	Nuclear and mitocondrial genomes. Chromosomes, genes and repetitive elements. Karyotypes and sizes of marine genomes. Nucleotide and structural variants of a genome. Genetic databases.
Applications of NGS technologies to marine genomes analyses	New technologies of genome ultrasequencing. Modalities of genome and transcriptome sequencing. Sequencing strategies for the identification of genomic variation. Identification and analysis of genomic variants. Genome sequencing applications to the study of marine organisms.
De novo generation of reference genomes	Strategies for reference genome sequencing. Scaffolding and estimation of assembly quality (value of the N50 parameter). Construction of genomic maps from NGS data. Annotation of a reference genome. Estimation of the size of a genome using a k-mers counting approach. Projects and databases of marine reference genomes.
Applications of genomics to marine life	Biodiversity and biogeography. Adaptative evolution. Effects of anthropogenic-induced changes in marine habitat. Genome evolution. Aquaculture and bioprospecting