Educational guide 2016_17 Facultade de Química

Contents

Topic	Sub-topic
Subject 1. Introduction: general appearances of Pharmaceutical Chemistry	Definitions, aims and scope of the Pharmaceutical Chemistry. Nomeclatura Of drugs and systems of classification. Agents quimioterápicos and agents *farmacodinámicos
Subject 2. Farmacological targets	Types of farmacological targets. You interact drug-target. Acids nucéicos, enzymes and proteinas like targets of drugs.
Subject 3. Receptors like targets of drugs	Types of receptors. Drugs agonistas, antagonistic and agonistas reverse. Measure and expression of the farmacological effect. Tachyphylaxis and tolerance
Subject 4. *Farmacocinética And appearances related	Absorption and transport through biological membranes, rules of Lipinski, biodisponibilidad. Metabolism, *profármacos. Excretion. Roads of administration and pharmaceutical forms.
Subject 5. Discovery, design and development of drugs	Strategies of research of heads of series, serendipia, sifted systematic, rational design. Farmacomodulación. Patents. Essays *preclinicos and clinical. Chemical development.
Subject 6. Strategies of design of drugs	Modelado Molecular, indirect methods (QSAR, design of fármacóforo), direct methods (docking).
Subject 7. Preparation, analysis and purification of drugs	Production in the pharmaceutical industry. Processes *fermentativos. Processed of drugs.