Guia docente 2023_24
Facultade de Bioloxía
Grado en Biología
 Subjects
  Integrative cell biology and physiology: Implications for health
   Contents
Topic Sub-topic
THEORETICAL CONTENTS

SECTION 1. Cellular homeostasis. Alterations and consequences in health.
Topic 1. Cellular stress. Causes of cellular stress and cell responses to maintain homeostasis. Apoptosis and autophagy.
Topic 2. Aging. Cellular basis of aging.
Topic 3. Cancer and microenvironment. Characteristics and behavior of tumor cells, and the influence of the environment.
Topic 4. Cell differentiation and tissue engraftment. Sources of stem cells. Types of stem cells. Cell differentiation. Extracellular matrices, properties. Decellularization. Applications: advantages and disadvantages.
SECTION 2. Body homeostasis. Adaptive responses and functional alterations Topic 5. Body homeostasis, health and disease. Homeostatic regulation. Disease: determining, conditioning and predisposing factors. Factors (physical, chemical, biological) causing disease. Adaptations to extreme conditions.
Topic 6. General adaptation syndrome and specific organic responses. Physiology of stress. Inflammation. Fever. Pain.
Topic 7. Energy homeostasis. Components of energy balance. Regulation of intake. Fasting and obesity.
Topic 8. Functional alterations of special relevance. Diabetes, Atherosclerosis. Hypo- and hypertension, cardiopathies, etc.
SECTION 3. Behavior and higher functions. Tema 9. Rhythmic physiology and chronobiology. Molecular and physiological bases of circadian rhythms.
Topic 10. Nervous bases of behavior. Encephalic mechanisms: limbic system and hypothalamus. Reward systems. States of consciousness: sleep.
PRACTICAL CONTENTS

Practical sessions that will be carried out in the laboratory and in which contents that reinforce and/or complement those provided in the other activities will be addressed.

Some of the possible activities that would be developed in the practical sessions are the following:

- Alterations in cell lines.
- Cytological and tissue characteristics of tumor tissue. Metastasis.
- Blood cell count and leukocyte formula. Hematic parameters.
- Blood pressure. Electrocardiogram.
- Circadian rhythm monitoring.
SEMINARS

Classroom sessions in which the resolution of experimental problems and case studies will be approached through work in small groups.
A list of topics and/or case studies will be provided for the students of each group to choose one and proceed to its development in the seminar sessions. Students will develop the skills of searching and categorizing information, as well presentation, defense and debate.
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